Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
Blog Article
one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the treatment method of various myeloma. Its synthesis or research is important for guaranteeing the purity and basic safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-one): A important compound during the synthesis of imatinib, a drug that targets precise forms of most cancers, which include Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers for instance breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their review is vital for optimizing the output approach and making sure higher purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is employed to deal with breast cancer, and these intermediates are linked to its generation.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor (3beta)- antagonist Employed in the remedy of breast cancer. Many intermediates help in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug productive in treating cancers for example ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the treatment of colorectal cancer and tiny cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, that have numerous programs, together with antiviral Qualities.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-four to regulate blood sugar degrees.
4. Miscellaneous Compounds
D-Gluconic 4 Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of assorted gluconic acid derivatives, which can be used in foods, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor within the synthesis of canagliflozin, a medication applied to manage kind two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).